Flower

Discovered and then isolated by a group of Italian scientists in late 2019, tetrahydrocannabutol (THCB) is a naturally occurring cannabinoid found in cannabis plants, similar to delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). It’s a compound that interacts with the endocannabinoid system (ECS) in the human body. Now, while THCB is a relatively lesser-known cannabinoid found in the cannabis plant, again it shares some similarities with delta-9-tetrahydrocannabinol (THC) and other cannabinoids. It also has unique properties.

THCB's chemical structure is similar to THC, with minor differences in the arrangement of atoms within the molecule. “THCB is a diterpenoid that’s 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group.”

Yes, THCB can be isolated or extracted from cannabis plants using various extraction methods. However, it’s less abundant in most cannabis strains compared to THC or CBD.

THCB is considered mildly psychoactive, but its psychoactive effects are generally weaker than THC. Users may experience some degree of euphoria or altered perception, but it is typically less potent. Still, you should not drive or operate any heavy machinery due to its psychoactive effects.

Research on THCB is limited, but it may have potential medical benefits, including anti-inflammatory, analgesic (pain-relieving), and neuroprotective properties. More research is needed to fully understand its therapeutic potential.

Like a good bulk of other cannabinoids, THCB may have side effects such as dry mouth, dry eyes, dizziness, and changes in mood or perception. However, these effects are typically less pronounced than those associated with THC.

THCB's legal status varies by location. In some regions, it may be considered a controlled substance, while in others, it may be legal for medical or recreational use. Here in the U.S., thanks to the 2018 Farm Bill, THCB is a legal cannabinoid on a federal level. However, as far as being legal on a per state basis, always check local laws and regulations.

THCB can interact with other cannabinoids and compounds in what is known as the "entourage effect”. This means its effects may be influenced by the presence of other cannabinoids, terpenes, and compounds in the cannabis plant.

THCB is structurally similar to THC but tends to have weaker psychoactive effects. It may also have distinct pharmacological properties and potential medical applications.

Since THCB is a relatively obscure cannabinoid, there’s limited information available about its potential drug interactions. It is advisable to consult with your physician if you’ve concerns about drug interactions.

THCB can be consumed in various forms, including smoking, vaping, dabbing, edibles (gummies mostly), tinctures, and the use of flower (loose buds or pre-rolls). The choice of consumption method can affect the onset and duration of its effects. Also, some products can contain mainly THCB or a nice combination of cannabinoids.

It is possible that THCB consumption could result in a positive drug test, as some drug tests are designed to detect THC metabolites. Always be aware of drug testing policies in your area if you are concerned about this.

When it comes to dosing, it’s best for those new to this cannabinoid who came from taking other cannabinoids to start low and slow, as they build up a tolerance. Generally, you should follow the instructions on the package, which will identify the right amount of THCB to take for the best results.

THCB is better suited for more experienced hemp users due to its effects.

There are no known cases of fatal overdose from THCB. However, consuming large amounts of THCB or any hemp-based products may lead to discomfort and adverse effects.