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Tetrahydrocannabutol is a naturally occurring cannabinoid that’s found in hemp. THC-B was only discovered in 2019, like we said before, by a group of Italian researchers who used advanced chromatography methods to take a deeper look into the chemical composition of cannabis. What they discovered was two previously unknown cannabinoids: THC-P (tetrahydrocannabiphorol) and THC-B.

As you might have guessed, THC-B is so new that there’s a lot we don’t know about it. You can imagine that it takes years to fully analyze a new cannabinoid, write a scientific report and have it published for the public to learn more. Cannabinoids like CBD and delta 8 THC were discovered decades ago, and that’s why we have such a wealth of information about them at our fingertips. THC-B is quickly becoming popular, however, so research on the cannabinoid’s effects should be available soon.

So, here’s what we do know. THC-B is a homologue of delta 9 THC and has a butyl side chain rather than a pentyl side chain that changes its chemical structure. In fact, this one change affects how the cannabinoid interacts with CB1 receptors – aka the cannabinoid receptors in the nervous system that cause a psychoactive response when we consume cannabinoids. It also plays a role in how the cannabinoid interacts with all cannabinoid receptors to yield distinctive effects throughout the body.

Basically, we are aware that THC-B works in a stronger manner with CB1 receptors than delta 9 THC, attaching to these receptors more efficiently, so to speak. As a result, THC-B has been determined to be more potent than delta 9, which’s something you will need to be aware of before you take it.

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